Careers

Balancing Passion with Purpose

At Equillium, everything we do centers around what’s best for patients — they are our reason for being, our driving force for excellence. We feel privileged to work in an industry where we have the opportunity to truly make a difference in the lives of others.

We embrace a culture that is defined by integrity, accountability, open communication, community, and respect for and appreciation of our diversity. We push each other to approach challenges with creativity and break from the expected — because only then does innovation happen.

Our Career Opportunities

Equillium is seeking individuals who want to make a difference in patients’ lives! Our current job opportunities are listed below.
 
Please submit resumes and cover letters to careers@equilliumbio.com.

Chief Medical Officer

Position: Chief Medical Officer

Position Level: Senior Executive

Reports to: Chief Executive Officer

Dept: Clinical Development

___________________________________________________________________________ 

Overview of Position:

Reporting to the Chief Executive Officer, the Chief Medical Officer will be a key member of the company’s executive team, which determines and sets the overall strategic direction of the company. The CMO will work closely with the executive team and provide leadership and direction for all clinical development programs in the company’s pipeline. The CMO will be responsible for the strategy, direction, and execution of the company’s clinical development plans.

Essential Duties & Responsibilities:

  • Responsible for all major phases of clinical development. Sets and directs the strategy for all clinical development activities. Establishes the conditions essential for determining the safety, efficacy, and marketability of product candidates.
  • Directs and/or contributes to all therapeutic product profiles to guide translational, clinical, and commercial development plans.
  • Directs and/or contributes to all companion diagnostic and biomarker strategies.
  • Orchestrate and manage regulatory strategies and interactions with Health Authorities.
  • Oversee the analysis and interpretation of clinical trial data and the reporting of clinical trial results.
  • Lead interactions with academic thought leaders, investigators, cooperative groups, and other clinical stakeholders.
  • Provide leadership to the executive team to develop and communicate the overall corporate strategy.
  • Active role representing the Company and its programs to external audiences, including the investment, medical and regulatory communities, as well as pharmaceutical or biotechnology industry collaborators/partners.
  • Responsible for hiring and managing appropriate full-, part time-, and/or contract personnel, including leadership in clinical research, pharmacology, biometrics, clinical operations, regulatory affairs, and drug safety and pharmacovigilance, as appropriate and agreed upon with the executive committee.

Job Requirements:

      Education: 

  • MD or equivalent with active board certification in hematology/oncology, rheumatology, immunology or other related sub-specialization.

      Experience:

  • 15 years minimum experience in pharmaceutical and/or biotechnology industry experience developing investigational new drugs and leading and building clinical development organizations.
  • Multiple years of management experience leading a clinical group including clinical/medical affairs, clinical operations, biometrics, regulatory affairs, and drug safety an pharmacovigilance.
  • Proven success record of executing Phase I-IV clinical development programs including successful regulatory submissions of IND’s, BLAs, NDAs MAAs leading to successfull marketing approvals
  • Knowledge of relevant FDA regulations and guidelines as well as those of the EU and other health authorities; experience in interactions with FDA is essential; experience in interactions with other health authorities strongly desired.
  • Experience with drug development in autoimmune and inflammatory diseases and/or oncology, and experience or knowledge of orphan disease drug development a plus.
  • Proven experience in translational medicine, clinical pharmacology and early stage development.
  • Excellent knowledge of the competitive environment for drugs in the autoimmune and inflammation, hematology/oncology, rheumatology and related therapeutic areas.

Skills and Attributes:

  • The successful candidate will read, write and speak fluent English, possess excellent communication skills and will be capable of articulating the Company’s clinical and regulatory strategies and progress to a wide audience including the CEO, the Board of Directors, Company employees, and the investor community.
  • Must have excellent leadership and interpersonal skills; should have proven skills as an effective team player who can engender credibility and confidence within and outside the company; must have outstanding executive presence.
  • Must be science- and data-driven.
  • For best fit, the candidate must have the ability and strong desire to be “hands on.” Must have a results-oriented work ethic and a positive, can-do attitude. Effective leadership, people management, communication skills and a team builder management style are essential.
  • Proven interpersonal and influencing skills. This includes a demonstrated ability to use an open and supportive communication style and to work cross functionally with multiple corporate sites, teams, and personalities.
  • Commitment to achieving corporate objectives while maintaining the highest ethical, regulatory, and scientific standards.
  • An entrepreneurial, innovative, energetic, hands-on, team oriented, and customer focused, attitude and approach.
  • The ability to think strategically as well as execute project details.
  • Ability and strong desire to work in a dynamic “start-up” environment and be able travel domestically and/or internationally.

Sr. Research Associate

Position: Sr. Research Associate

Level:  Associate

Reports to:  Director of Research

Dept: Research

___________________________________________________________________________ 

Overview of Position:

This position will be an integral part of our research team working on advancing our understanding of the CD6-ALCAM pathway.  The candidate will participate in designing and executing pre-clinical and translational research projects. Candidate is expected to perform experiments using cellular, biochemical, and molecular based approaches, organize and analyze results, and communicate findings in team meetings. Will be integral in establishing laboratory standard operating procedures and general protocols. Laboratory work will involve samples from human and animal (mouse, primate). May be asked to perform other scientifically-related duties as needed.

Essential Duties & Responsibilities:

Internal Scientific Duties

  • Performs a variety of laboratory procedures, including cell-based and biochemical assays, using both new and established methods and techniques under general guidance
  • Conducts experiments and data analyses, and interprets results
  • Assist in upkeep of a small laboratory
  • Experimental design to address both mechanistic and disease-based questions and hypotheses
  • Organize and maintain data files and reports
  • Conduct literature reviews and attend seminars to keep up-to-date on topics relevant to research at Equillium
  • Communicate results at research and cross-functional meetings

External Scientific  Duties

  • Provide input on study designs to be performed with external CROs and academic collaborations.

Job Requirements:

      Education: 

  • Bachelor’s degree in a scientific discipline with at least 3 years relevant work experience or MS in related discipline with 1 year relevant work experience

      Experience:

  • >3 years of laboratory experience. Experience in cellular immunology and associated techniques is essential.
  • Experience in biotech industry not required but a strong plus
  • Some flow cytometry experience, preparation of samples, staining with appropriate markers for immuno-phenotyping; analysis of flow data using appropriate software
  • Experience in tissue culture (both primary cells and cell lines) and cell-based assays is required
  • Experience with both ELISA-based assays and multiplex cytokine assays (Luminex, MSD and/or CBA
  • The candidate must be well organized and able to work on multiple concurrent projects

Skills and Attributes:

  • Highly self-motivated
  • Detail-oriented with excellent time management and organizational skills
  • Proven ability to manage multiple tasks and associated deadlines
  • Some amount of scheduling flexibility in order to accommodate experimental needs.
  • Exceptional communication and interpersonal skills. Able to present scientific findings at cross-team meetings.
  • Strong computer literacy, including Microsoft Office suite and Graphpad Prism, as well as flow cytometry analysis software such as FlowJo.
  • Flexibility to adapt in a cross-functional and dynamic, “start-up” type environment.

Director/Sr. Director, Clinical Development

Position: Director/Sr. Director, Clinical Development

Position Level: Director

Reports to: Chief Medical Officer & VP,  Clinical Development

___________________________________________________________________________ 

Overview of Position:

The primary objective of this position will be to serve as the lead for specific clinical development programs within Clinical Development and have direct contributions across all of the programs. This position will be responsible for directing and leading cross-functional clinical research activities for EQ001, focusing on advancing clinical development programs through all phases of development, including contributing to and participating in regulatory submissions and meetings, taking a lead role in submission of INDs/BLAs and contributing to the strategy and execution of lifecycle planning for EQ001. This role will be accountable for matrix deliverables carried by team projects within the broader clinical development team (internal/external). Examples of matrix team projects include the design, execution, and reporting of clinical trials, analysis of clinical and safety data at the conclusion of each phase of development including BLA/NDA submissions, contributing to medical affairs activities including KOL identification and management, advisory boards, and medical communication activities including publications, pharmacovigilance activities, and translational research and commercial projects. Key measures of success will include the ability to drive, coordinate and harmonize clinical development activities with multiple functional groups with the intent of delivering success by defining clear strategic development plans, communicating timelines and deliverables, ensuring appropriate accountabilities, and demonstrating an ability to lead teams/groups in hitting product development milestones.

Essential Duties & Responsibilities:

  • Primary responsibility for the planning and execution of clinical research activities for relevant programs.
  • Provides clinical input in regulatory documents: INDs, BLAs/NDAs, PSURs; Annual Safety Reports, Core Data Sheets, Investigator’s Brochures, Clinical Study Reports, Clinical Summaries and Clinical Overviews (risk/benefit evaluation).
  • Collaborates with clinical, regulatory, and commercial organizations to develop EQ001 lifecycle plans, including new indications.
  • Supports the VP, Clinical Development in presenting recommendations and securing senior leadership endorsement of clinical research plans and managing the communications on projects by monitoring and providing status update reports on key development projects from inception through implementation.

Job Requirements:

      Education: 

  • B.S. in Life Sciences and M.D. or PhD or Pharm D required

      Experience:

  • Proven track record of exemplary leadership, high standards of professionalism and successful management of complex drug development projects within an integrated, high performing biotechnology or specialty pharmaceutical organization.
  • In addition, this person will have previously served a minimum of 3-5 years in an integrative team leadership role where they were tasked with specific drug development projects, within clinical drug development and safety, global registration, and post-approval activities.
  • It is preferred that the candidate have clinical development experience in areas of autoimmune and inflammatory diseases and in this role.
  • The person will have provided strategic and operational leadership, implemented results-driven processes and gleaned the requisite experience in working collaboratively with both the research and commercial ends of the drug development spectrum. Other key candidate qualifications include:
    • Results-oriented drug development professional in developing and implementing global clinical development programs.
    • A strong technical and commercial orientation coupled with a track record of successfully integrating Research and Development and Commercial teams by providing thought and operational leadership and valuable input to both development and commercially marketed programs.
    • Ability to think strategically including the ability to set project goals and establish measures of success.
    • An understanding of standard industry practices pertaining to Good Clinical Practice/ICH guidelines on the conduct of clinical research.
    • General knowledge of US/EU drug safety and pharmacovigilance reporting requirements.
    • Experience in data analysis and medical evaluation of clinical trial data.
    • Hands on experience on regulatory submissions involving clinical trial data.

Skills and Attributes:

  • Proven intrapersonal and influencing skills.  This includes a demonstrated ability to use an open and supportive communication style and to work cross functionally with multiple corporate sites and different personalities.
  • A combination of both solid business and sharp scientific acumen along with very strong presentation skills and the ability to listen and communicate to a wide variety of scientific and commercially oriented individuals.
  • Pragmatic and analytical in his/her thinking and the ability take a reasoned position based on the integration of a diverse set of inputs.
  • High energy level and a positive outlook coupled with the requisite “can do” attitude and a willingness to do what it takes to achieve personal and organizational goals and overcome obstacles.
  • High degree of professionalism, ethics and honesty with the ability to serve as a credible and passionate champion for Equillium’s breakthrough therapies.
  • Strong computer literacy, including Microsoft Excel, Word, and most importantly the use of Power Point.
  • Flexibility to adapt in a cross-functional and dynamic, “start-up” type environment.
  • Domestic and/or international travel requirement – up to 25%.

(Sr.) Clinical Research Associate

Position: (Sr.) Clinical Research Associate

Position Level: Associate

Reports to: Clinical Operations

___________________________________________________________________________ 

Overview of Position:

Under minimal supervision in Clinical Operations, works with the team to coordinate the activities associated with the evaluation, initiation and management of clinical trials and study sites. May assist in managing clinical studies including site and/or vendor oversight.

Essential Duties & Responsibilities:

  • Assist with study site CDAs, feasibility, and selection
  • Coordinates and assists with the activities associated with site start-up and overall study site management, including review of site documents in anticipation of site activation and site oversight through close-out
  • Review and management of site documents
  • Review, tracking and documentation of monitoring reports
  • Identification and escalation of issues and assists with corrective action plans
  • Provides review and input on study-specific plans
  • Coordinates the review and content of study materials such as eCRFs, study guides and site/subject instructions
  • Assists with the preparation, conduct and presentations for CRA Training
  • May assist with coordination and management of study site budgets
  • Manages the overall site investigational product accountability and reconciliation process
  • Assists with the review and oversight of data (EDC and vendor data) for quality (e.g. ensures CRF data queries are resolved and data reconciles, i.e. AEs and Medical History to con meds)
  • Coordinates CRO tracking, and training, including lab samples
  • eTMF support and management; assurance of ongoing document maintenance and completion of study files, checking eTMF and assisting with loading documents and follow-up on missing items. Must be able to identify what documents should be posted in the eTMF per study status and manage to fulfillment.
  • Builds CRO relationships and provides oversight on vendor performance
  • Assists with program oversight, identifies deficiencies and risks, and assists with improvement and mitigation plans
  • Ensures compliance with Equillium policies and procedures
  • Intermittent clinical site monitoring for adherence to protocol and GCP
  • May complete site visits in assistance of CRO and to promote timeline
  • Review of clinical protocols and amendments, as needed
  • Other duties as assigned

Job Requirements:

      Education: 

  • BA/BS in Biological Sciences or related field, or BSN/RN

      Experience:

  • 5 years (2-3 years for CRA) related experience in life sciences or medically related field, including 4 years of experience in industry within Clinical Development (Sr. CRA)
  • Experience with development of prospective site-selection criteria
  • Protocol input experience
  • Familiar with advanced concepts of clinical research
  • Ability to deal with time demands, incomplete information or unexpected events
  • Experience with interactions with outside vendors (i.e. sites, CROs, contract labs) and all functions of clinical research
  • Experience with reviewing adequacy of site-proposed documents for compliance with relevant regulations

Skills and Attributes:

  • Attention to detail
  • Excellent time management and organizational skills
  • Proven ability to manage multiple tasks and associated deadlines
  • Exceptional and timely communication and interpersonal skills
  • Strong computer literacy, including: SharePoint, Microsoft Excel, Word, Outlook and PowerPoint
  • Flexibility to adapt in a cross-functional and dynamic, “start-up” type environment
  • Travel required 10-50%, as needed

Sr. Clinical Trial Manager

Position: Sr. Clinical Trial Manager

___________________________________________________________________________ 

Overview of Position:

Managing and meeting the objectives of clinical studies and programs by ensuring the successful conduct of assigned clinical programs consistent with applicable regulations, Good Clinical Practice (GCP), and current standard operating procedures (SOPs). Accountable for meeting clinical study and milestones within scope and budget. Interface effectively with various clinical service providers. Establish working practices that promote and maintain a culture of inspection readiness at all times. Lead and provide oversight of operations activities of the project(s) and/or program(s).

Essential Duties & Responsibilities:

      Clinical Operations and Clinical Study Project Management:

  • Lead clinical operations activities in the preparation and coordination of clinical trial set-up, maintenance and closure in accordance with GCP and SOPs.
  • Provide study management by interfacing with representatives from key functional groups such as: Clinical Development, Data Management, Statistics, Regulatory Affairs, QA, Medical Writing, CMC, and Research.
  • Actively support other functional groups with clinical trial set-up, maintenance and closure (e.g. data management, statistics, medical writing, clinical trial material vendors, etc.).
  • Provide expertise and direction on the activities involved with planning, conducting and reporting of clinical data.
  • Lead trial initiation activities including protocol development, activities for investigator site selection and regulatory preparedness, investigator budget and contract negotiation and clinical vendor procurement activities.
  • Ensure overall study progress including development and maintenance of timelines, risk mitigation and contingency plans for all aspects of trial conduct, and management of study scope and change control.
  • Actively engage in study, oversight to monitor adherence to GCP with timely and appropriate escalation of issues as necessary.
  • Participate in the development and review of regulatory documents as appropriate.
  • Conduct site clinical site monitoring activities as needed.
  • Other duties as assigned.

      Vendor Management:

  • Meet with and gather information on new vendors to build a knowledge base and maintain an understanding of available services.
  • Complete vendor proposal requests in conjunction with the contracts and outsourcing team as required and actively participate in the review and selection process of clinical vendors.
  • Ensure adherence to business processes with respect to vendor contracts and invoicing procedures.
  • Serve as the key liaison with project and site management clinical research organizations (CROs) and monitor and track adherence to contracts and budgets.
  • Participate in quarterly trial budget reviews and invoice reconciliation.

      Quality and Process Improvement:

  • Participate in the development and review of clinical SOPs.
  • Maintain 100% compliance with SOP training.
  • Conduct audits and inspection readiness visits to investigator sites and vendors.
  • Promote and lead process improvement initiatives consistent with GCP operations and project management tools and concepts.

Job Requirements:

      Education: 

  • BA/BS in Biological Sciences or related field, or BSN/RN.

      Experience:

  • 5-8 years related experience in life sciences or medically related field, including 3 years of experience in the industry within Clinical Operations (i.e. Manager level).
  • Experience with development of prospective site-selection criteria.
  • Practical experience in initiating, maintaining, and terminating clinical trials.
  • Previous experience in leading cross-functional teams.
  • Protocol development experience.
  • Familiar with advanced concepts of clinical research.
  • Ability to deal with time demands, incomplete information or unexpected events.
  • Experience with management of CROs or other vendor relationships.
  • Experience with administration of budgets and grants.
  • Experience with reviewing the adequacy of site-proposed documents for compliance with relevant regulations.
  • Experience managing Clinical Research Associates.
  • Previously conducted or managed trials in autoimmune and inflammatory conditions desired.

Skills and Attributes:

  • Attention to detail.
  • Excellent time management and organizational skills.
  • Proven ability to manage multiple tasks and associated deadlines.
  • Exceptional and timely communication and interpersonal skills.
  • Strong computer literacy, including Microsoft Excel, Word, Outlook, and PowerPoint.
  • Flexibility to adapt in a cross-functional and dynamic, “start-up” type environment.
  • Travel required 20-30%.

Equillium’s recruitment and employment process is managed by Human Resources and all candidates must be submitted through Human Resources. Recruiters are requested to not contact our hiring managers or employees directly to inquire about open positions or present candidates, but instead to contact Human Resources.

Human Resources will review and keep all resumes submitted on file.

Equillium is proud to be an Equal Opportunity Employer.

Our Benefits

As part of the biotech industry, Equillium understands and recognizes the importance of providing quality health and financial benefits to employees that are competitive and will support healthy living.

Health Benefits

  • Medical Insurance Plans – including HMO, PPO and HSA options
  • Dental Insurance
  • Vision Insurance

Life Benefits

  • Life Insurance and AD&D
  • Supplemental Employee and Dependent Life Insurance
  • Annual Holidays
  • Unlimited Vacation Time
  • Annual Sick Time
  • Employee Assistance Program
  • Travel Assistance Program

Financial Benefits

  • 401(k) Plan
  • Annual Bonus
  • Stock Options
  • Employee Stock Purchase Plan